| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
|---|
| Ligand | BDBM50302823 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_595294 (CHEMBL1047088) |
|---|
| IC50 | 1910±n/a nM |
|---|
| Citation |  Liu, J; Fu, Z; Wang, Y; Schmitt, M; Huang, A; Marshall, D; Tonn, G; Seitz, L; Sullivan, T; Lucy Tang, H; Collins, T; Medina, J Discovery and optimization of CRTH2 and DP dual antagonists. Bioorg Med Chem Lett19:6419-23 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin D2 receptor |
|---|
| Name: | Prostaglandin D2 receptor |
|---|
| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40288.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13258 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
|
|
|
|---|
| BDBM50302823 |
|---|
| n/a |
|---|
| Name | BDBM50302823 |
|---|
| Synonyms: | 2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylcarbamoyl)phenoxy)-3-ethoxyphenyl)acetic acid | CHEMBL569719 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H24Cl2N2O7S |
|---|
| Mol. Mass. | 567.438 |
|---|
| SMILES | CCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OCC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
