| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 6 |
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| Ligand | BDBM50209663 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_595742 (CHEMBL1045265) |
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| EC50 | >10000±n/a nM |
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| Citation |  Das, A; Ko, H; Burianek, LE; Barrett, MO; Harden, TK; Jacobson, KA Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem53:471-80 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 6 |
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| Name: | P2Y purinoceptor 6 |
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| Synonyms: | P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36452.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1511151 |
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| Residue: | 328 |
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| Sequence: | MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTR
TAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDL
SPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARM
AVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPIL
FYFTQKKFRRRPHELLQKLTAKWQRQGR
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| BDBM50209663 |
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| n/a |
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| Name | BDBM50209663 |
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| Synonyms: | CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alpha-D-glucopyranosyl ester 2-((4'-thio)uridin-5''-yl) ester |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N2O16P2S |
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| Mol. Mass. | 582.367 |
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| SMILES | OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=S)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O |
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| Structure | 
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