| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic Anhydrase XIV |
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| Ligand | BDBM50303489 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_595960 |
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| Ki | 3200±n/a nM |
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| Citation |  Maresca A; Temperini C; Pochet L; Masereel B; Scozzafava A; Supuran CT Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem 53:335-44 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic Anhydrase XIV |
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| Name: | Carbonic Anhydrase XIV |
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| Synonyms: | CA-XIV | Carbonate dehydratase XIV | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 37665.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme. |
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| Residue: | 337 |
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| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
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| BDBM50303489 |
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| n/a |
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| Name | BDBM50303489 |
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| Synonyms: | 6-methoxy-2-oxo-2H-chromene-3-carboxylic acid | CHEMBL568416 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8O5 |
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| Mol. Mass. | 220.1782 |
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| SMILES | COc1ccc2oc(=O)c(cc2c1)C(O)=O |
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| Structure | 
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