Reaction Details |
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Target | Carbonic anhydrase 15 |
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Ligand | BDBM50303495 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_595961 (CHEMBL1044463) |
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Ki | 6600±n/a nM |
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Citation | Maresca, A; Temperini, C; Pochet, L; Masereel, B; Scozzafava, A; Supuran, CT Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem53:335-44 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Carbonic anhydrase 15 |
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Name: | Carbonic anhydrase 15 |
Synonyms: | CAH15_MOUSE | Ca15 | Car15 |
Type: | PROTEIN |
Mol. Mass.: | 35484.02 |
Organism: | Mus musculus |
Description: | ChEMBL_651955 |
Residue: | 324 |
Sequence: | MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
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BDBM50303495 |
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n/a |
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Name | BDBM50303495 |
Synonyms: | CHEMBL568385 | ethyl 7-methoxy-2-oxo-2H-chromene-3-carboxylate |
Type | Small organic molecule |
Emp. Form. | C13H12O5 |
Mol. Mass. | 248.2314 |
SMILES | CCOC(=O)c1cc2ccc(OC)cc2oc1=O |
Structure |
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