| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 3 |
|---|
| Ligand | BDBM50303487 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_595951 (CHEMBL1044453) |
|---|
| Ki | 9000±n/a nM |
|---|
| Citation |  Maresca, A; Temperini, C; Pochet, L; Masereel, B; Scozzafava, A; Supuran, CT Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem53:335-44 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 3 |
|---|
| Name: | Carbonic anhydrase 3 |
|---|
| Synonyms: | CA-III | CA3 | CAH3_HUMAN | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29562.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human cloned isozyme. |
|---|
| Residue: | 260 |
|---|
| Sequence: | MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL
VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP
SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL
VSNWRPPQPINNRVVRASFK
|
|
|
|---|
| BDBM50303487 |
|---|
| n/a |
|---|
| Name | BDBM50303487 |
|---|
| Synonyms: | 7-phenethoxy-2H-chromen-2-one | CHEMBL567544 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14O2 |
|---|
| Mol. Mass. | 250.2919 |
|---|
| SMILES | O=c1ccc2ccc(CCc3ccccc3)cc2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
