| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50303488 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_595956 (CHEMBL1044458) |
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| Ki | 32±n/a nM |
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| Citation |  Maresca, A; Temperini, C; Pochet, L; Masereel, B; Scozzafava, A; Supuran, CT Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem53:335-44 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50303488 |
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| n/a |
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| Name | BDBM50303488 |
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| Synonyms: | 6-methyl-2-oxo-2H-chromene-3-carboxylic acid | CHEMBL577123 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8O4 |
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| Mol. Mass. | 204.1788 |
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| SMILES | Cc1ccc2oc(=O)c(cc2c1)C(O)=O |
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| Structure | 
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