| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50303996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_595422 (CHEMBL1040063) |
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| Ki | >500±n/a nM |
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| Citation |  de la Fuente, T; Martín-Fontecha, M; Sallander, J; Benhamú, B; Campillo, M; Medina, RA; Pellissier, LP; Claeysen, S; Dumuis, A; Pardo, L; López-Rodríguez, ML Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation. J Med Chem53:1357-69 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50303996 |
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| n/a |
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| Name | BDBM50303996 |
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| Synonyms: | CHEMBL568329 | Phenyl(4-piperazin-1-yl-1H-benzimidazol-2-yl)methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N4O |
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| Mol. Mass. | 306.3617 |
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| SMILES | O=C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccccc1 |
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| Structure | 
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