| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NAD-dependent protein deacetylase HST2 |
|---|
| Ligand | BDBM50304355 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_606807 (CHEMBL1068571) |
|---|
| Ki | 2500±n/a nM |
|---|
| Citation |  Sanders, BD; Jackson, B; Brent, M; Taylor, AM; Dang, W; Berger, SL; Schreiber, SL; Howitz, K; Marmorstein, R Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorg Med Chem17:7031-41 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NAD-dependent protein deacetylase HST2 |
|---|
| Name: | NAD-dependent protein deacetylase HST2 |
|---|
| Synonyms: | HST2 | HST2_YEAST | NAD-dependent deacetylase HST2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39972.79 |
|---|
| Organism: | Saccharomyces cerevisiae |
|---|
| Description: | ChEMBL_533704 |
|---|
| Residue: | 357 |
|---|
| Sequence: | MSVSTASTEMSVRKIAAHMKSNPNAKVIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKL
PYPEAVFDVDFFQSDPLPFYTLAKELYPGNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTL
ERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSKLAEHPIKDFVKCDVCGELVKPA
IVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPR
KVKRVLCNLETVGDFKANKRPTDLIVHQYSDEFAEQLVEELGWQEDFEKILTAQGGMGDN
SKEQLLEIVHDLENLSLDQSEHESADKKDKKLQRLNGHDSDEDGASNSSSSQKAAKE
|
|
|
|---|
| BDBM50304355 |
|---|
| n/a |
|---|
| Name | BDBM50304355 |
|---|
| Synonyms: | 3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methylbenzyl)phenol | CHEMBL594863 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H9Cl5O2 |
|---|
| Mol. Mass. | 386.485 |
|---|
| SMILES | Cc1cc(Cl)c(O)c(Cc2c(O)c(Cl)cc(Cl)c2Cl)c1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
