Reaction Details | |||
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Target | D(1A) dopamine receptor | ||
Ligand | BDBM50010686 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_603130 (CHEMBL1038852) | ||
Ki | 35.7±n/a nM | ||
Citation | Schulze, M; Müller, FK; Mason, JM; Görls, H; Lehmann, J; Enzensperger, C Dibenzazecine scaffold rebuilding--is the flexibility always essential for high dopamine receptor affinities? Bioorg Med Chem17:6898-907 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
D(1A) dopamine receptor | |||
Name: | D(1A) dopamine receptor | ||
Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | ||
Type: | Enzyme | ||
Mol. Mass.: | 49303.43 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P21728 | ||
Residue: | 446 | ||
Sequence: |
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BDBM50010686 | |||
n/a | |||
Name | BDBM50010686 | ||
Synonyms: | (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium | (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | 10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX) | 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL25856 | dihydrexidine | ||
Type | Small organic molecule | ||
Emp. Form. | C17H17NO2 | ||
Mol. Mass. | 267.3224 | ||
SMILES | Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O | ||
Structure |