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TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI
LigandBDBM7459
Substrate/Competitorn/a
Meas. Tech.ChEMBL_603807 (CHEMBL1042945)
Ki 7050±n/a nM
Citation Yao, J; Zhang, Q; Min, J; He, J; Yu, Z Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. Bioorg Med Chem Lett20:56-9 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Name:Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Synonyms:Enoyl - (acyl carrier protein) reductase | Enoyl-ACP Reductase (FabI) | Enoyl-[acyl-carrier-protein] reductase | Enoyl-acyl carrier protein reductase (FabI) | FABI_ECOLI | NADH-dependent enoyl-ACP reductase | envM | fabI
Type:Enzyme
Mol. Mass.:27861.12
Organism:Escherichia coli
Description:n/a
Residue:262
Sequence:
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIV
LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDIS
SYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPE
GVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI
SGEVVHVDGGFSIAAMNELELK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM7459
n/a
NameBDBM7459
Synonyms:2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one | CHEMBL151 | Luteolin (27) | Luteolin (4) | acs.jmedchem.1c00409_ST.600 | cid_5280445 | luteolin | med.21724, Compound 3
TypeSmall organic molecule
Emp. Form.C15H10O6
Mol. Mass.286.2363
SMILESOc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1
Structure
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