| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Myelin-associated glycoprotein |
|---|
| Ligand | BDBM50378603 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_611876 (CHEMBL1070831) |
|---|
| Kd | 2400±n/a nM |
|---|
| Citation |  Mesch, S; Moser, D; Strasser, DS; Kelm, A; Cutting, B; Rossato, G; Vedani, A; Koliwer-Brandl, H; Wittwer, M; Rabbani, S; Schwardt, O; Kelm, S; Ernst, B Low molecular weight antagonists of the myelin-associated glycoprotein: synthesis, docking, and biological evaluation. J Med Chem53:1597-615 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Myelin-associated glycoprotein |
|---|
| Name: | Myelin-associated glycoprotein |
|---|
| Synonyms: | MAG_MOUSE | Mag | Siglec-4a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 69368.91 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_663794 |
|---|
| Residue: | 627 |
|---|
| Sequence: | MIFLATLPLFWIMISASRGGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWY
FNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGD
LGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGL
GEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPP
VIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGED
GVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIF
KEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESH
CAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNETEREFVYSERSGLLLTSILTIRGQA
QAPPRVICTSRNLYGTQSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKK
NVTESSSFSGGDNPHVLYSPEFRISGAPDKYESEKQRLGSERRLLGLRGESPELDLSYSH
SDLGKRPTKDSYTLTEELAEYAEIRVK
|
|
|
|---|
| BDBM50378603 |
|---|
| n/a |
|---|
| Name | BDBM50378603 |
|---|
| Synonyms: | CHEMBL600189 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H26ClF2N2O9 |
|---|
| Mol. Mass. | 571.932 |
|---|
| SMILES | CC(=O)N[C@@H]1[C@@H](O)C[C@](OCc2cccc(F)c2F)(O[C@H]1[C@H](O)[C@@H](O)CNC(=O)c1ccc(Cl)cc1)C([O-])=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
