| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 2 |
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| Ligand | BDBM50423646 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_610353 (CHEMBL1072085) |
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| Ki | 34100±n/a nM |
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| Citation |  Robertson, CR; Scholl, EA; Pruess, TH; Green, BR; White, HS; Bulaj, G Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery. J Med Chem53:1871-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 2 |
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| Name: | Galanin receptor type 2 |
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| Synonyms: | GALR2_RAT | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galnr2 | Galr2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40697.04 |
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| Organism: | RAT |
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| Description: | Galanin R2 GALR2 RAT::O08726 |
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| Residue: | 372 |
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| Sequence: | MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTT
NLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVS
LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWS
APRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIII
VAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR
KGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPN
CTASSRTLDPAC
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| BDBM50423646 |
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| n/a |
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| Name | BDBM50423646 |
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| Synonyms: | CHEMBL2309599 | Galnon |
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| Type | Small organic molecule |
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| Emp. Form. | C40H46N4O6 |
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| Mol. Mass. | 678.8164 |
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| SMILES | Cc1cc(=O)oc2cc(NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc34)ccc12 |r| |
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| Structure | 
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