| Reaction Details |
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 | Report a problem with these data |
| Target | Fibroblast growth factor 2 |
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| Ligand | BDBM50307400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_610686 (CHEMBL1072347) |
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| Kd | 82±n/a nM |
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| Citation |  Johnstone, KD; Karoli, T; Liu, L; Dredge, K; Copeman, E; Li, CP; Davis, K; Hammond, E; Bytheway, I; Kostewicz, E; Chiu, FC; Shackleford, DM; Charman, SA; Charman, WN; Harenberg, J; Gonda, TJ; Ferro, V Synthesis and biological evaluation of polysulfated oligosaccharide glycosides as inhibitors of angiogenesis and tumor growth. J Med Chem53:1686-99 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fibroblast growth factor 2 |
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| Name: | Fibroblast growth factor 2 |
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| Synonyms: | Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2 |
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| Type: | Protein |
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| Mol. Mass.: | 30803.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09038 |
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| Residue: | 288 |
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| Sequence: | MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAA
GSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAA
PAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDG
RVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERL
ESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
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| BDBM50307400 |
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| n/a |
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| Name | BDBM50307400 |
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| Synonyms: | CHEMBL604366 | hexadecasodium [3-({4-[(4-{[3,5-bis(sulfonatooxy)-6-[(sulfonatooxy)methyl]-4-{[3,4,5-tris(sulfonatooxy)-6-[(sulfonatooxy)methyl]oxan-2-yl]oxy}oxan-2-yl]oxy}-3,5-bis(sulfonatooxy)-6-[(sulfonatooxy)methyl]oxan-2-yl)oxy]-3,5-bis(sulfonatooxy)-6-[(sulfonatooxy)methyl]oxan-2-yl}oxy)-2-(octyloxy)-5-(sulfonatooxy)-6-[(sulfonatooxy)methyl]oxan-4-yl] sulfate |
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| Type | Small organic molecule |
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| Emp. Form. | C38H52O74S16 |
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| Mol. Mass. | 2205.824 |
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| SMILES | CCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| |
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| Structure | 
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