| Reaction Details |
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 | Report a problem with these data |
| Target | 5'-nucleotidase |
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| Ligand | BDBM7460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_612633 (CHEMBL1065670) |
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| Ki | 45.3±n/a nM |
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| Citation |  Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Müller, CE Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. J Med Chem53:2076-86 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5'-nucleotidase |
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| Name: | 5'-nucleotidase |
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| Synonyms: | 5'-nucleotidase | 5NTD_RAT | Ecto-5'-nucleotidase (e5'NT) | Ecto-5-nucleotidase (e5'NT) | NT | Nt5 | Nt5e | Nte |
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| Type: | Enzyme |
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| Mol. Mass.: | 63971.44 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P21588 |
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| Residue: | 576 |
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| Sequence: | MRPAAATAPKWLLLALSALLPLWPTAKSWELTIMHTNDVHSRLEQTSDDSTKCLNASLCV
GGVARLFTKVQQIRKEEPNVLLLDAGDQYQGTIWFTVYKGLEVAHFMNLLGYDAMALGNH
EFDNGVEGLIDPLLRNVKFPILSANIKARGPLAPQISGLYLPYKVLSVGGEVVGIVGYTS
KETPFLSNPGTNLVFEDEVTALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDV
VVGGHTNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDDKG
NVVTSYGNPILLNSTIREDAAIKADINQWRIKLDNYSTQELGRTIVYLNGSAQECRFREC
NMGNLICDAMINNNLRHPDEMFWNHVSMCIVNGGGIRSPIDERNNGTITWENLAAVLPFG
GTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDISRKPWDRVVQLKVLCTK
CRVPIYEPLEMDKVYKVVLPSYLVNGGDGFQMIKDELLKHDSGDQDISVVSEYISKMKVI
YPAVEGRIKFSAASHYQGSFPLIILSFWAVILVLYQ
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| BDBM7460 |
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| n/a |
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| Name | BDBM7460 |
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| Synonyms: | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate | CHEMBL50 | Quercetin | Quercetin (10) | Quercetin (21) | Quercetin (Qur) | US11021454, Compound Quercetin | US9180183, Quercetin | med.21724, Compound 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O7 |
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| Mol. Mass. | 302.2357 |
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| SMILES | Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O |
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| Structure | 
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