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TargetNucleoside triphosphate diphosphohydrolase 3
LigandBDBM50268574
Substrate/Competitorn/a
Meas. Tech.ChEMBL_612641
Ki 1500±n/a nM
Citation Baqi YLee SYIqbal JRipphausen PLehr AScheiff ABZimmermann HBajorath JMüller CE Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. J Med Chem 53:2076-86 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Nucleoside triphosphate diphosphohydrolase 3
Name:Nucleoside triphosphate diphosphohydrolase 3
Synonyms:Ectonucleoside triphosphate diphosphohydrolase 3, isoform CRA_a | Protein Entpd3
Type:PROTEIN
Mol. Mass.:59110.31
Organism:Rattus norvegicus
Description:ChEMBL_612641
Residue:529
Sequence:
MFTVMTRQPCEQAGFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIHHPQVLSPGLKYGIV
LDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCMLKV
KEQVPKHLHESTRVYLGATAGMRLLRLQNETAAHEVLESIQSYFKSQPFDFRGAQIISGQ
EEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVSEEKMEPNAS
DTVQVSLYGYTYTLYTHSFQCYGRNEAEKKFLAMLLQSPSTDANISNPCYPHGYSTTFTM
GHVFGSLCTEKQRPKSYNPSDTITFTGTGDPQLCREKVASVFDFSACQEQDACSFDGIYQ
PKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPSLLPRFDETYARS
YCFSAHYIYHLLINGYKFTEATWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIQL
PIQPPVFMGVLAFFTAIALLCLAFLFYLCSAFRTKERSENAFDQAVDSD
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  Blast E-value cutoff:
BDBM50268574
n/a
NameBDBM50268574
Synonyms:CHEMBL498423 | Sodium 1-Amino-4-(1-naphthylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate | Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10 dihydroanthracene-2-sulfonate
TypeSmall organic molecule
Emp. Form.C24H15N2O5S
Mol. Mass.443.452
SMILESNc1c2C(=O)c3ccccc3C(=O)c2c(Nc2cccc3ccccc23)cc1S([O-])(=O)=O
Structure
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