| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50055810 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_608751 (CHEMBL1067764) |
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| Ki | 3.6±n/a nM |
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| Citation |  Neves, G; Menegatti, R; Antonio, CB; Grazziottin, LR; Vieira, RO; Rates, SM; Noël, F; Barreiro, EJ; Fraga, CA Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors. Bioorg Med Chem18:1925-35 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50055810 |
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| n/a |
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| Name | BDBM50055810 |
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| Synonyms: | 1-Phenyl-4-(2-phenyl-3H-imidazol-4-ylmethyl)-piperazine | 1-phenyl-4-((2-phenyl-1H-imidazol-4-yl)methyl)piperazine | CHEMBL103871 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22N4 |
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| Mol. Mass. | 318.4155 |
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| SMILES | C(N1CCN(CC1)c1ccccc1)c1cnc([nH]1)-c1ccccc1 |
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| Structure | 
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