| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-glucosidase MAL12 |
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| Ligand | BDBM50308256 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_613790 (CHEMBL1069561) |
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| IC50 | 3800±n/a nM |
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| Citation |  Ferreira, SB; Sodero, AC; Cardoso, MF; Lima, ES; Kaiser, CR; Silva, FP; Ferreira, VF Synthesis, biological activity, and molecular modeling studies of 1H-1,2,3-triazole derivatives of carbohydrates as alpha-glucosidases inhibitors. J Med Chem53:2364-75 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-glucosidase MAL12 |
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| Name: | Alpha-glucosidase MAL12 |
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| Synonyms: | α-Glucosidase | MAL12 | MAL12_YEAST | MAL1S | Maltase | alpha-Glucosidase (α-Glucosidase) |
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| Type: | Protein |
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| Mol. Mass.: | 68084.32 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | P53341 |
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| Residue: | 584 |
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| Sequence: | MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCP
FYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFK
ESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASR
QVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHP
NWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF
THVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADD
SPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSF
GKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQ
ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNF
SGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
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| BDBM50308256 |
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| n/a |
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| Name | BDBM50308256 |
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| Synonyms: | 1-O-Methyl-2,3-O-isopropylidene-5-(4-cyclohexene-1H-1,2,3-triazol-1-yl)-beta-D-ribofuranose | CHEMBL598823 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25N3O4 |
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| Mol. Mass. | 335.3981 |
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| SMILES | CO[C@@H]1O[C@H](Cn2cc(nn2)C2=CCCCC2)[C@H]2OC(C)(C)O[C@@H]12 |r,t:12| |
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| Structure | 
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