| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50079652 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_613366 (CHEMBL1068173) |
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| Ki | 0.550000±n/a nM |
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| Citation |  Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem18:2195-203 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_MOUSE | Adenosine A1 receptor | Adenosine receptor A1 | Adora1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36646.06 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_479902 |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSEVEQAWIANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIEEDIPEEKADD
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| BDBM50079652 |
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| n/a |
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| Name | BDBM50079652 |
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| Synonyms: | (E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(2-phenyl-pyrazolo[1,5-a]pyridin-3-yl)-propenone | (R)-1-(2-(2-hydroxyethyl)piperidin-1-yl)-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one | 1-[2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(2-phenyl-pyrazolo[1,5-a]pyridin-3-yl)-propenone | CHEMBL440115 | FK-453 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25N3O2 |
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| Mol. Mass. | 375.4635 |
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| SMILES | OCC[C@H]1CCCCN1C(=O)\C=C\c1c(nn2ccccc12)-c1ccccc1 |
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| Structure | 
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