| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50079654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_613366 (CHEMBL1068173) |
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| Ki | 10±n/a nM |
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| Citation |  Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem18:2195-203 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_MOUSE | Adenosine A1 receptor | Adenosine receptor A1 | Adora1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36646.06 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_479902 |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSEVEQAWIANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIEEDIPEEKADD
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| BDBM50079654 |
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| n/a |
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| Name | BDBM50079654 |
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| Synonyms: | 4-(6-oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-1(6H)-yl)butanoic acid | 4-[6-Oxo-3-(2-phenyl-pyrazolo[1,5-a]pyridin-3-yl)-6H-pyridazin-1-yl]-butyric acid | CHEMBL292917 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N4O3 |
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| Mol. Mass. | 374.3926 |
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| SMILES | OC(=O)CCCn1nc(ccc1=O)-c1c(nn2ccccc12)-c1ccccc1 |
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| Structure | 
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