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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A1 | ||
| Ligand | BDBM50308507 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_613353 (CHEMBL1074290) | ||
| Ki | 2.5±n/a nM | ||
| Citation |  Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem18:2195-203 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A1 | |||
| Name: | Adenosine receptor A1 | ||
| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 36704.13 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | n/a | ||
| Residue: | 326 | ||
| Sequence: |
| ||
| BDBM50308507 | |||
| n/a | |||
| Name | BDBM50308507 | ||
| Synonyms: | 4-(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol | CHEMBL592435 | SLV-320 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H20N4O | ||
| Mol. Mass. | 308.3776 | ||
| SMILES | OC1CCC(CC1)Nc1nc(nc2[nH]ccc12)-c1ccccc1 |(25.44,4.86,;24.11,4.15,;24.1,2.61,;22.77,1.85,;21.43,2.63,;21.43,4.16,;22.77,4.93,;20.1,1.87,;20.1,.33,;18.77,-.45,;18.78,-1.98,;20.11,-2.75,;21.42,-1.98,;22.89,-2.46,;23.8,-1.22,;22.9,.03,;21.44,-.44,;17.45,-2.75,;16.11,-1.99,;14.78,-2.75,;14.78,-4.3,;16.11,-5.07,;17.45,-4.3,)| | ||
| Structure | 
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