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TargetCell division control protein 42 homolog
LigandBDBM50308877
Substrate/Competitorn/a
Meas. Tech.ChEMBL_607696 (CHEMBL1066161)
IC50>5000±n/a nM
Citation Morwick, TBüttner, FHCywin, CLDahmann, GHickey, EJakes, SKaplita, PKashem, MAKerr, SKugler, SMao, WMarshall, DPaw, ZShih, CKWu, FYoung, E Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase. J Med Chem53:759-77 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cell division control protein 42 homolog
Name:Cell division control protein 42 homolog
Synonyms:CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:PROTEIN
Mol. Mass.:21258.36
Organism:Homo sapiens (Human)
Description:ChEMBL_652970
Residue:191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
EPKKSRRCVLL
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BDBM50308877
n/a
NameBDBM50308877
Synonyms:3,4-Dimethoxy-N-[3-(2-piperidin-4-yl-ethylcarbamoyl)-benzyl]-benzamide | CHEMBL604085
TypeSmall organic molecule
Emp. Form.C24H31N3O4
Mol. Mass.425.5206
SMILESCOc1ccc(cc1OC)C(=O)NCc1cccc(c1)C(=O)NCCC1CCNCC1
Structure
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