| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50309029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_612941 (CHEMBL1070893) |
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| Ki | 368±n/a nM |
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| Citation |  Scott, JD; Li, SW; Wang, H; Xia, Y; Jayne, CL; Miller, MW; Duffy, RA; Boykow, GC; Kowalski, TJ; Spar, BD; Stamford, AW; Chackalamannil, S; Lachowicz, JE; Greenlee, WJ Diaryl piperidines as CB1 receptor antagonists. Bioorg Med Chem Lett20:1278-83 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50309029 |
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| n/a |
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| Name | BDBM50309029 |
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| Synonyms: | (3R,6S)-1-(4-chlorophenyl)-N-cyclohexyl-6-(2,4-dichlorophenyl)piperidine-3-sulfonamide | CHEMBL607977 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27Cl3N2O2S |
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| Mol. Mass. | 501.897 |
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| SMILES | Clc1ccc(cc1)N1C[C@@H](CC[C@H]1c1ccc(Cl)cc1Cl)S(=O)(=O)NC1CCCCC1 |r| |
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| Structure | 
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