| Reaction Details |
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 | Report a problem with these data |
| Target | Succinyl-diaminopimelate desuccinylase |
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| Ligand | BDBM21642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_617887 (CHEMBL1101552) |
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| IC50 | 3300±n/a nM |
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| Citation |  Gillner, D; Armoush, N; Holz, RC; Becker, DP Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. Bioorg Med Chem Lett19:6350-2 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Succinyl-diaminopimelate desuccinylase |
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| Name: | Succinyl-diaminopimelate desuccinylase |
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| Synonyms: | DAPE_HAEIN | dapE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41343.05 |
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| Organism: | Haemophilus influenzae |
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| Description: | ChEMBL_617887 |
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| Residue: | 377 |
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| Sequence: | MKEKVVSLAQDLIRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEP
VIAFAGHTDVVPTGDENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANP
NHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRG
SITGNLYIQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAG
TGSNNVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGK
LLDSITSAIEETIGITPKAETGGGTSDGRFIALMGAEVVEFGPLNSTIHKVNECVSVEDL
GKCGEIYHKMLVNLLDS
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| BDBM21642 |
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| n/a |
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| Name | BDBM21642 |
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| Synonyms: | (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid | CHEMBL1560 | Capozide | Captopril | Lopirin | SQ 14,225 | SQ14534 | US11491146, Compound L-Captopril |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15NO3S |
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| Mol. Mass. | 217.285 |
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| SMILES | C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O |
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| Structure | 
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