| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Succinyl-diaminopimelate desuccinylase |
|---|
| Ligand | BDBM50099857 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_617887 (CHEMBL1101552) |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Gillner, D; Armoush, N; Holz, RC; Becker, DP Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. Bioorg Med Chem Lett19:6350-2 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Succinyl-diaminopimelate desuccinylase |
|---|
| Name: | Succinyl-diaminopimelate desuccinylase |
|---|
| Synonyms: | DAPE_HAEIN | dapE |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41343.05 |
|---|
| Organism: | Haemophilus influenzae |
|---|
| Description: | ChEMBL_617887 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MKEKVVSLAQDLIRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEP
VIAFAGHTDVVPTGDENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANP
NHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRG
SITGNLYIQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAG
TGSNNVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGK
LLDSITSAIEETIGITPKAETGGGTSDGRFIALMGAEVVEFGPLNSTIHKVNECVSVEDL
GKCGEIYHKMLVNLLDS
|
|
|
|---|
| BDBM50099857 |
|---|
| n/a |
|---|
| Name | BDBM50099857 |
|---|
| Synonyms: | ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsaeure | Acethydroxamsaure | Acetic acid, oxime | Acetylhydroxamic acid | Cetohyroxamic acid | Lithostat | Methylhydroxamic acid | N-Acetyl hydroxyacetamide | N-Acetylhydroxylamine | N-Hydroxyacetamide | acetohydroxamic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C2H5NO2 |
|---|
| Mol. Mass. | 75.0666 |
|---|
| SMILES | CC(=O)NO |
|---|
| Structure | 
|
|---|
Search and Browse
