| Reaction Details |
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 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SETD7 |
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| Ligand | BDBM50378739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_627737 (CHEMBL1116159) |
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| IC50 | 2500±n/a nM |
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| Citation |  Dowden, J; Hong, W; Parry, RV; Pike, RA; Ward, SG Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases. Bioorg Med Chem Lett20:2103-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone-lysine N-methyltransferase SETD7 |
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| Name: | Histone-lysine N-methyltransferase SETD7 |
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| Synonyms: | Histone-lysine N-methyltransferase SETD7 | KIAA1717 | KMT7 | SET domain-containing protein 7/9 (Set7/9) | SET7 | SET9 | SETD7 | SETD7_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 40691.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WTS6 |
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| Residue: | 366 |
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| Sequence: | MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE
GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW
IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP
HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT
VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT
PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF
QATQQK
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| BDBM50378739 |
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| n/a |
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| Name | BDBM50378739 |
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| Synonyms: | SINEFUNGIN | jm2c00120, Sinefungin |
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| Type | Small organic molecule |
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| Emp. Form. | C15H23N7O5 |
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| Mol. Mass. | 381.387 |
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| SMILES | N[C@@H](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| |
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| Structure | 
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