| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-2 |
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| Ligand | BDBM50314986 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_623928 (CHEMBL1108053) |
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| Ki | 1400000±n/a nM |
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| Citation |  Chavas, LM; Kato, R; Suzuki, N; von Itzstein, M; Mann, MC; Thomson, RJ; Dyason, JC; McKimm-Breschkin, J; Fusi, P; Tringali, C; Venerando, B; Tettamanti, G; Monti, E; Wakatsuki, S Complexity in influenza virus targeted drug design: interaction with human sialidases. J Med Chem53:2998-3002 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-2 |
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| Name: | Sialidase-2 |
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| Synonyms: | Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42256.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960638 |
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| Residue: | 380 |
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| Sequence: | MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYD
APTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRAN
VTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYA
YRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHL
RARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTH
SWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYE
EIVFLMFTLKQAFPAEYLPQ
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| BDBM50314986 |
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| n/a |
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| Name | BDBM50314986 |
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| Synonyms: | (2S,3R,4R)-3-acetamido-2-(2,3-dihydroxypropoxy)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid | CHEMBL1090839 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17NO8 |
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| Mol. Mass. | 291.2546 |
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| SMILES | CC(=O)N[C@@H]1[C@H](O)C=C(O[C@@H]1OCC(O)CO)C(O)=O |r,c:7| |
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| Structure | 
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