| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50316692 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632470 (CHEMBL1108334) |
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| Ki | 0.09±n/a nM |
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| Citation |  Mésangeau, C; Pérès, B; Descamps-François, C; Chavatte, P; Audinot, V; Coumailleau, S; Boutin, JA; Delagrange, P; Bennejean, C; Renard, P; Caignard, DH; Berthelot, P; Yous, S Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands. Bioorg Med Chem18:3426-36 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50316692 |
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| n/a |
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| Name | BDBM50316692 |
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| Synonyms: | CHEMBL1094212 | N-[2-(7-{4-(4'-Hydroxymethylbiphenyl-4-yloxy}butoxy)-naphthalen-1-yl)ethyl]acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33NO4 |
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| Mol. Mass. | 483.598 |
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| SMILES | CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(cc3)-c3ccc(CO)cc3)cc12 |
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| Structure | 
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