| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prolyl endopeptidase |
|---|
| Ligand | BDBM50316820 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_632258 (CHEMBL1110120) |
|---|
| Ki | 2100±n/a nM |
|---|
| Citation |  Lawandi, J; Gerber-Lemaire, S; Juillerat-Jeanneret, L; Moitessier, N Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors. J Med Chem53:3423-38 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prolyl endopeptidase |
|---|
| Name: | Prolyl endopeptidase |
|---|
| Synonyms: | PE | PPCE_BOVIN | PREP | Post-proline cleaving enzyme |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 80630.39 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_632258 |
|---|
| Residue: | 710 |
|---|
| Sequence: | MLSFQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIR
GLYKERMTELYDYPKYSCNFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVCLDPNTLS
DDGTVALRGYAFSEDGEYVAYGLSASGSDWVTIKFMKVDGAKELADVLERVKFSCMAWTH
DGKGMFYNAYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAEL
SDDGRYVLLSIREGCDPVNRLWYCDLHQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVF
TFKTNRHSPNYRLINIDFTDPEESRWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNT
LQLHDMATGALLKTFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPR
VFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISI
TPNYSVCRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKE
GYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYG
CSDNKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSPKFIATLQHLV
GRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIQ
|
|
|
|---|
| BDBM50316820 |
|---|
| n/a |
|---|
| Name | BDBM50316820 |
|---|
| Synonyms: | (S)-benzyl 2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate | CHEMBL1088406 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H22N2O3 |
|---|
| Mol. Mass. | 302.3682 |
|---|
| SMILES | O=C(OCc1ccccc1)N1CCC[C@H]1C(=O)N1CCCC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
