| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
|---|
| Ligand | BDBM50167367 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_635035 (CHEMBL1118586) |
|---|
| Ki | 749±n/a nM |
|---|
| Citation |  Di Fiore, A; Monti, SM; Innocenti, A; Winum, JY; De Simone, G; Supuran, CT Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. Bioorg Med Chem Lett20:3601-5 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 6 |
|---|
| Name: | Carbonic anhydrase 6 |
|---|
| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35371.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P23280 |
|---|
| Residue: | 308 |
|---|
| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
|
|
|
|---|
| BDBM50167367 |
|---|
| n/a |
|---|
| Name | BDBM50167367 |
|---|
| Synonyms: | (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylsulfamide | CHEMBL190447 | N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]aminosulfonamide | N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H19BN2O4S |
|---|
| Mol. Mass. | 298.166 |
|---|
| SMILES | CC1(C)OB(OC1(C)C)c1ccc(NS(N)(=O)=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
