| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50320771 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639158 (CHEMBL1167419) |
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| IC50 | 7120±n/a nM |
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| Citation |  Wen, WH; Wang, SY; Tsai, KC; Cheng, YS; Yang, AS; Fang, JM; Wong, CH Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. Bioorg Med Chem18:4074-84 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | NA | NRAM_I33A0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49687.56 |
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| Organism: | Influenza A virus |
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| Description: | ChEMBL_1347422 |
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| Residue: | 453 |
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| Sequence: | MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVA
GQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQ
GALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGIS
GPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIF
KIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGY
ICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWD
PNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETI
WTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
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| BDBM50320771 |
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| n/a |
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| Name | BDBM50320771 |
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| Synonyms: | 5-Acetamido-2,6-anhydro-4-[N-(3-carboxypropyl)guanidino]-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid | CHEMBL1164186 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26N4O9 |
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| Mol. Mass. | 418.399 |
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| SMILES | CC(=O)N[C@H]1[C@@H](OC(=C[C@@H]1N(CCCC(O)=O)C(N)=N)C(O)=O)[C@H](O)[C@H](O)CO |r,c:7| |
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| Structure | 
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