| Reaction Details |
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 | Report a problem with these data |
| Target | Membrane-bound transcription factor site-1 protease |
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| Ligand | BDBM50378788 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_641529 (CHEMBL1175363) |
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| Ki | 125000±n/a nM |
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| Citation |  Basak, A; Mitra, D; Das, AK; Mohottalage, D; Basak, A C(2)-Symmetric azobenzene-amino acid conjugates and their inhibition of Subtilisin Kexin Isozyme-1. Bioorg Med Chem Lett20:3977-81 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Membrane-bound transcription factor site-1 protease |
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| Name: | Membrane-bound transcription factor site-1 protease |
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| Synonyms: | KIAA0091 | MBTP1_HUMAN | MBTPS1 | S1P | SKI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 117773.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_641529 |
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| Residue: | 1052 |
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| Sequence: | MKLVNIWLLLLVVLLCGKKHLGDRLEKKSFEKAPCPGCSHLTLKVEFSSTVVEYEYIVAF
NGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDH
PNIKRVTPQRKVFRSLKYAESDPTVPCNETRWSQKWQSSRPLRRASLSLGSGFWHATGRH
SSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNE
RTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKK
IDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGG
IDFEDNIARFSSRGMTTWELPGGYGRMKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVV
AGAVTLLVSTVQKRELVNPASMKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYKP
QASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQ
NGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAE
QTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTN
FRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSL
VIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTL
ANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGR
IVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERM
EGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKV
VLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQ
INKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV
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| BDBM50378788 |
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| n/a |
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| Name | BDBM50378788 |
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| Synonyms: | CHEMBL1170116 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H44N4O8 |
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| Mol. Mass. | 708.7994 |
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| SMILES | CC(C)[C@H](NC(=O)COc1ccccc1\N=N\c1ccccc1OCC(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 |r| |
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| Structure | 
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