| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50321526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639627 (CHEMBL1175305) |
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| IC50 | 12±n/a nM |
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| Citation |  Cheung, AW; Brinkman, J; Firooznia, F; Flohr, A; Grimsby, J; Gubler, ML; Guertin, K; Hamid, R; Marcopulos, N; Norcross, RD; Qi, L; Ramsey, G; Tan, J; Wen, Y; Sarabu, R 4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: drug-like and non-xanthine based A2B adenosine receptor antagonists. Bioorg Med Chem Lett20:4140-6 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50321526 |
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| n/a |
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| Name | BDBM50321526 |
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| Synonyms: | CHEMBL1171897 | N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-fluorobenzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18FN3O3S |
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| Mol. Mass. | 387.428 |
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| SMILES | CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(F)cc3)sc12 |
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| Structure | 
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