| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50321816 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_643317 (CHEMBL1177488) |
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| Ki | >1000±n/a nM |
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| Citation |  Ishikawa, M; Furuuchi, T; Yamauchi, M; Yokoyama, F; Kakui, N; Sato, Y Synthesis and structure-activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor. Bioorg Med Chem18:5441-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50321816 |
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| n/a |
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| Name | BDBM50321816 |
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| Synonyms: | 4-((1H-Imidazol-4-yl)methyl)-1-(4-methoxyphenyl)piperidine | CHEMBL1172775 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N3O |
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| Mol. Mass. | 271.3574 |
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| SMILES | COc1ccc(cc1)N1CCC(Cc2cnc[nH]2)CC1 |
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| Structure | 
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