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TargetCarbonic anhydrase 15
LigandBDBM11641
Substrate/Competitorn/a
Meas. Tech.ChEMBL_643935
Ki 34±n/a nM
Citation Avvaru BSWagner JMMaresca AScozzafava ARobbins AHSupuran CTMcKenna R Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg Med Chem Lett 20:4376-81 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 15
Name:Carbonic anhydrase 15
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:35484.02
Organism:Mus musculus
Description:ChEMBL_651955
Residue:324
Sequence:
MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM11641
n/a
NameBDBM11641
Synonyms:1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyridiniumperchlorate | 2,4,6-trimethyl-1-[2-(4-sulfamoylphenyl)ethyl]pyridin-1-ium perchlorate | CHEMBL352535 | Compound 10 | pyridinium deriv. 10
TypeSmall organic molecule
Emp. Form.C16H21N2O2S
Mol. Mass.305.415
SMILESCc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1
Structure
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