| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 15 |
|---|
| Ligand | BDBM11641 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_643935 (CHEMBL1211834) |
|---|
| Ki | 34±n/a nM |
|---|
| Citation |  Avvaru, BS; Wagner, JM; Maresca, A; Scozzafava, A; Robbins, AH; Supuran, CT; McKenna, R Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. Bioorg Med Chem Lett20:4376-81 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 15 |
|---|
| Name: | Carbonic anhydrase 15 |
|---|
| Synonyms: | CAH15_MOUSE | Ca15 | Car15 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35484.02 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_651955 |
|---|
| Residue: | 324 |
|---|
| Sequence: | MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRL
VQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQ
LHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDR
DNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVL
WTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSS
VSTLPCLHLALVGLGVGLRLWQGP
|
|
|
|---|
| BDBM11641 |
|---|
| n/a |
|---|
| Name | BDBM11641 |
|---|
| Synonyms: | 1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyridiniumperchlorate | 2,4,6-trimethyl-1-[2-(4-sulfamoylphenyl)ethyl]pyridin-1-ium perchlorate | CHEMBL352535 | Compound 10 | pyridinium deriv. 10 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21N2O2S |
|---|
| Mol. Mass. | 305.415 |
|---|
| SMILES | Cc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
