| Reaction Details |
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 | Report a problem with these data |
| Target | Transcriptional activator protein LuxR |
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| Ligand | BDBM20607 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_643998 (CHEMBL1211897) |
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| IC50 | 40000±n/a nM |
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| Citation |  Soulère, L; Sabbah, M; Fontaine, F; Queneau, Y; Doutheau, A LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones. Bioorg Med Chem Lett20:4355-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcriptional activator protein LuxR |
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| Name: | Transcriptional activator protein LuxR |
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| Synonyms: | LUXR_ALIFS | luxR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28563.86 |
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| Organism: | Vibrio fischeri |
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| Description: | ChEMBL_831639 |
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| Residue: | 250 |
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| Sequence: | MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILD
NYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLIT
GFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSN
NDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILT
GAIDCPYFKN
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| BDBM20607 |
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| n/a |
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| Name | BDBM20607 |
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| Synonyms: | (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine | 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine | CHEMBL83 | FOSTRIECIN SODIUM | NCGC00024928 | Nolvadex | Tamoxifen | Tamoxifen (8) | Tamoxifen, 7 | cid_2733526 | med.21724, Compound Tamoxifen |
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| Type | Small organic molecule |
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| Emp. Form. | C26H29NO |
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| Mol. Mass. | 371.5146 |
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| SMILES | CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 |
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| Structure | 
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