| Reaction Details |
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 | Report a problem with these data |
| Target | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Ligand | BDBM50326219 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_659591 (CHEMBL1248886) |
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| Ki | <1000±n/a nM |
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| Citation |  Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B Discovery of N-{1-[3-(3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): an allosteric muscarinic M1 receptor agonist with unprecedented selectivity and procognitive potential. J Med Chem53:6386-97 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Synonyms: | Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Type: | Protein |
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| Mol. Mass.: | 25917.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16083 |
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| Residue: | 231 |
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| Sequence: | MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
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| BDBM50326219 |
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| n/a |
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| Name | BDBM50326219 |
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| Synonyms: | 4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one | CHEMBL1242950 | CHEMBL2206334 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H31NO |
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| Mol. Mass. | 301.4662 |
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| SMILES | CCCCC1CCN(CCCC(=O)c2ccccc2C)CC1 |
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| Structure | 
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