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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Peptidyl-prolyl cis-trans isomerase B | ||
| Ligand | BDBM50330184 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_676204 (CHEMBL1273324) | ||
| IC50 | 20.6±n/a nM | ||
| Citation |  Scribner, A; Houck, D; Huang, Z; Mosier, S; Peel, M; Scorneaux, B Synthesis and biological evaluation of [D-lysine]8cyclosporin A analogs as potential anti-HCV agents. Bioorg Med Chem Lett20:6542-6 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Peptidyl-prolyl cis-trans isomerase B | |||
| Name: | Peptidyl-prolyl cis-trans isomerase B | ||
| Synonyms: | CYP-S1 | CYPB | Cyclophilin B | Cyclophilin B (CypB) | PPIB | PPIB_HUMAN | PPIase | Peptidyl-prolyl cis-trans isomerase B | Rotamase | S-cyclophilin | SCYLP | ||
| Type: | Protein | ||
| Mol. Mass.: | 23751.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P23284 | ||
| Residue: | 216 | ||
| Sequence: |
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| BDBM50330184 | |||
| n/a | |||
| Name | BDBM50330184 | ||
| Synonyms: | CHEMBL1269582 | N-(4-((2R,5S,8S,11S,14S,17S,23S,26S,29S,32S)-17-ethyl-14-((1R,2R)-1-hydroxy-2-methylhex-4-enyl)-5,8,23,29-tetraisobutyl-11,26-diisopropyl-4,7,10,13,19,22,28,32-octamethyl-3,6,9,12,15,18,21,24,27,30,33-undecaoxo-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2-yl)butyl)pivalamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C70H126N12O13 | ||
| Mol. Mass. | 1343.822 | ||
| SMILES | CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](CCCCNC(=O)C(C)(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |r| | ||
| Structure | 
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