| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-1 |
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| Ligand | BDBM4994 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_679987 (CHEMBL1280935) |
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| IC50 | >10000000±n/a nM |
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| Citation |  Hata, K; Koseki, K; Yamaguchi, K; Moriya, S; Suzuki, Y; Yingsakmongkon, S; Hirai, G; Sodeoka, M; von Itzstein, M; Miyagi, T Limited inhibitory effects of oseltamivir and zanamivir on human sialidases. Antimicrob Agents Chemother52:3484-91 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-1 |
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| Name: | Sialidase-1 |
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| Synonyms: | NANH | NEU1 | NEUR1_HUMAN | Sialidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45463.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960639 |
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| Residue: | 415 |
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| Sequence: | MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM
EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST
WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS
WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW
RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD
TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET
VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
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| BDBM4994 |
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| n/a |
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| Name | BDBM4994 |
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| Synonyms: | (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | CHEMBL674 | GS4071 | Oseltamivir carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H24N2O4 |
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| Mol. Mass. | 284.3514 |
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| SMILES | CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O |r,c:7| |
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| Structure | 
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