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TargetMBT domain-containing protein 1
LigandBDBM35938
Substrate/Competitorn/a
Meas. Tech.ChEMBL_684951 (CHEMBL1286366)
IC50 34000±n/a nM
Citation Kireev, DWigle, TJNorris-Drouin, JHerold, JMJanzen, WPFrye, SV Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds. J Med Chem53:7625-31 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
MBT domain-containing protein 1
Name:MBT domain-containing protein 1
Synonyms:MBT domain-containing protein 1 | MBT domain-containing protein 1 (MBTD1) | MBTD1 | MBTD1_HUMAN
Type:Protein
Mol. Mass.:70557.67
Organism:Homo sapiens (Human)
Description:n/a
Residue:628
Sequence:
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMV
GVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYA
QYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEV
PNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGK
PLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLC
RTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQ
DGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGID
GSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPV
KLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCE
SPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELL
DGEDYNFLQGASDQESNGSANFYIKQEP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM35938
n/a
NameBDBM35938
Synonyms:1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine | 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane | 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine | 5-HT,N-ACETYL | CHEMBL505 | CHLORPHENIRAMINE | CHLORPHENIRAMINE MALEATE | Polaramin | Polaramine | Polaronil | [3H]Chlorphenamine | [3H]Chlorpheniramine | chlorophenylpyridamine | chlorphenamine | clorfeniramina | d-Chlorpheniramine | gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine | gamma-(4-chlorophenyl)-gamma-(2-pyridyl)propyldimethylamine
Typeradiolabeled ligand
Emp. Form.C16H19ClN2
Mol. Mass.274.788
SMILESCN(C)CCC(c1ccc(Cl)cc1)c1ccccn1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: