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TargetSialidase 3
LigandBDBM4706
Substrate/Competitorn/a
Meas. Tech.ChEMBL_687673
IC50 43000±n/a nM
Citation Zou YAlbohy ASandbhor MCairo CW Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid. Bioorg Med Chem Lett 20:7529-33 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sialidase 3
Name:Sialidase 3
Synonyms:Sialidase-3
Type:PROTEIN
Mol. Mass.:48257.99
Organism:Homo sapiens (Human)
Description:ChEMBL_461856
Residue:428
Sequence:
MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRR
GLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSG
RNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYT
YYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVL
YCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSS
KDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRP
WILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGR
NPSQFKSN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM4706
n/a
NameBDBM4706
Synonyms:(2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid | 2,3-didehydro-2-deoxy-N-acetylneuraminic acid | CHEMBL96712 | DANA | Neu5Ac2en
TypeSmall organic molecule
Emp. Form.C11H17NO8
Mol. Mass.291.2546
SMILESCC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O |r,c:7|
Structure
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