| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50324028 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_717377 (CHEMBL1670099) |
|---|
| Ki | 2300±n/a nM |
|---|
| Citation |  Balboni, G; Salvadori, S; Marczak, ED; Knapp, BI; Bidlack, JM; Lazarus, LH; Peng, X; Si, YG; Neumeyer, JL Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic. Eur J Med Chem46:799-803 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50324028 |
|---|
| n/a |
|---|
| Name | BDBM50324028 |
|---|
| Synonyms: | (S)-2-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid | CHEMBL1214049 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H28N2O4 |
|---|
| Mol. Mass. | 396.4794 |
|---|
| SMILES | CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
