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TargetSteroid hormone receptor ERR1
LigandBDBM50336753
Substrate/Competitorn/a
Meas. Tech.ChEMBL_718350 (CHEMBL1679770)
IC50 47±n/a nM
Citation Patch, RJSearle, LLKim, AJDe, DZhu, XAskari, HBO'Neill, JCAbad, MCRentzeperis, DLiu, JKemmerer, MLin, LKasturi, JGeisler, JGLenhard, JMPlayer, MRGaul, MD Identification of diaryl ether-based ligands for estrogen-related receptora as potential antidiabetic agents. J Med Chem54:788-808 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Steroid hormone receptor ERR1
Name:Steroid hormone receptor ERR1
Synonyms:ERR-alpha | ERR1 | ERR1_HUMAN | ESRL1 | ESRRA | Estrogen receptor-like 1 | Estrogen-Related Receptor, alpha | Estrogen-related receptor alpha | NR3B1 | Nuclear receptor subfamily 3 group B member 1 | Steroid hormone receptor ERR1 | Steroid hormone receptor ERR1 alpha | Steroid hormone receptor ERR1/Estrogen-related receptor alpha (ERRa) | von Hippel-Lindau disease tumor suppressor/Steroid hormone receptor ERR1
Type:PROTEIN
Mol. Mass.:45508.08
Organism:Homo sapiens (Human)
Description:ChEMBL_1499891
Residue:423
Sequence:
MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
MMD
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  Blast E-value cutoff:
BDBM50336753
n/a
NameBDBM50336753
Synonyms:4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-chlorobenzoic Acid Methyl Ester | CHEMBL1671964
TypeSmall organic molecule
Emp. Form.C19H14ClNO6S
Mol. Mass.419.836
SMILESCOC(=O)c1ccc(Oc2ccc(C=C3SC(O)=NC3=O)cc2OC)c(Cl)c1 |w:13.12,c:17|
Structure
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