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TargetP2X purinoceptor 4
LigandBDBM50268874
Substrate/Competitorn/a
Meas. Tech.ChEMBL_718658 (CHEMBL1680809)
IC50>10000±n/a nM
Citation Baqi, YHausmann, RRosefort, CRettinger, JSchmalzing, GMüller, CE Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. J Med Chem54:817-30 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 4
Name:P2X purinoceptor 4
Synonyms:P2RX4_RAT | P2rx4 | Purinergic, P2X4
Type:Enzyme Catalytic Domain
Mol. Mass.:43504.16
Organism:RAT
Description:Purinergic, P2X4 0 RAT::P51577
Residue:388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIP
DKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKKYYYRDKKYKYVEDYEQGLSGEMNQ
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  Blast E-value cutoff:
BDBM50268874
n/a
NameBDBM50268874
Synonyms:CHEMBL499580 | Sodium 1-Amino-4-[3-(4,6-dichloro-[1,3,5]triazine-2-ylamino)-5-carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
TypeSmall organic molecule
Emp. Form.C24H13Cl2N6O7S
Mol. Mass.600.368
SMILESNc1c(cc(Nc2cc(Nc3nc(Cl)nc(Cl)n3)cc(c2)C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O
Structure
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