| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 2 |
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| Ligand | BDBM50262422 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_718656 (CHEMBL1680807) |
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| IC50 | 4000±n/a nM |
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| Citation |  Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Müller, CE Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. J Med Chem54:817-30 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 2 |
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| Name: | P2X purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RX2_RAT | P2X purinoceptor 2 | P2X2 | P2X2/P2X3 receptor | P2rx2 | Purinergic receptor | Purinergic, P2X2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52625.55 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X2 0 RAT::P49653 |
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| Residue: | 472 |
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| Sequence: | MVRRLARGCWSAFWDYETPKVIVVRNRRLGFVHRMVQLLILLYFVWYVFIVQKSYQDSET
GPESSIITKVKGITMSEDKVWDVEEYVKPPEGGSVVSIITRIEVTPSQTLGTCPESMRVH
SSTCHSDDDCIAGQLDMQGNGIRTGHCVPYYHGDSKTCEVSAWCPVEDGTSDNHFLGKMA
PNFTILIKNSIHYPKFKFSKGNIASQKSDYLKHCTFDQDSDPYCPIFRLGFIVEKAGENF
TELAHKGGVIGVIINWNCDLDLSESECNPKYSFRRLDPKYDPASSGYNFRFAKYYKINGT
TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSIGVGSFLCDWILLTFMNKNK
LYSHKKFDKVRTPKHPSSRWPVTLALVLGQIPPPPSHYSQDQPPSPPSGEGPTLGEGAEL
PLAVQSPRPCSISALTEQVVDTLGQHMGQRPPVPEPSQQDSTSTDPKGLAQL
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| BDBM50262422 |
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| n/a |
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| Name | BDBM50262422 |
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| Synonyms: | CHEMBL477339 | sodium (E)-4-((3-formyl-4-hydroxy-5-methyl-2-(phosphonatooxymethyl)phenyl)diazenyl)benzene-1,3-disulfonate |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11N2O12PS2 |
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| Mol. Mass. | 506.36 |
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| SMILES | Cc1cc(N=Nc2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O |w:4.3| |
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| Structure | 
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