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TargetP2X purinoceptor 4
LigandBDBM50336788
Substrate/Competitorn/a
Meas. Tech.ChEMBL_718658 (CHEMBL1680809)
IC50>10000±n/a nM
Citation Baqi, YHausmann, RRosefort, CRettinger, JSchmalzing, GMüller, CE Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. J Med Chem54:817-30 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 4
Name:P2X purinoceptor 4
Synonyms:P2RX4_RAT | P2rx4 | Purinergic, P2X4
Type:Enzyme Catalytic Domain
Mol. Mass.:43504.16
Organism:RAT
Description:Purinergic, P2X4 0 RAT::P51577
Residue:388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIP
DKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKKYYYRDKKYKYVEDYEQGLSGEMNQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50336788
n/a
NameBDBM50336788
Synonyms:CHEMBL404450 | sodium 1-amino-9,10-dioxo-4-(p-tolylamino)-9,10-dihydroanthracene-2-sulfonate | sodium 4-(p-toluidino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
TypeSmall organic molecule
Emp. Form.C21H15N2O5S
Mol. Mass.407.42
SMILESCc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc1
Structure
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