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TargetDelta-type opioid receptor
LigandBDBM50341291
Substrate/Competitorn/a
Meas. Tech.ChEMBL_742587 (CHEMBL1769430)
Ki 140±n/a nM
Citation Zhang, TYan, ZSromek, AKnapp, BIScrimale, TBidlack, JMNeumeyer, JL Aminothiazolomorphinans with mixed¿ andµ opioid activity. J Med Chem54:1903-13 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50341291
n/a
NameBDBM50341291
Synonyms:CHEMBL1766029 | N'-Phenyl-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan
TypeSmall organic molecule
Emp. Form.C27H31N3S
Mol. Mass.429.62
SMILESC(C1CC1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1cc2sc(Nc4ccccc4)nc2cc31 |r,TLB:0:4:15.30.14:12|
Structure
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