| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50341296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_742590 (CHEMBL1769433) |
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| Ki | 610±n/a nM |
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| Citation |  Zhang, T; Yan, Z; Sromek, A; Knapp, BI; Scrimale, T; Bidlack, JM; Neumeyer, JL Aminothiazolomorphinans with mixed¿ andµ opioid activity. J Med Chem54:1903-13 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50341296 |
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| n/a |
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| Name | BDBM50341296 |
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| Synonyms: | CHEMBL1766034 | N'-(Pyridin-2-yl)-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N4S |
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| Mol. Mass. | 430.608 |
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| SMILES | C(C1CC1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1cc2sc(Nc4ccccn4)nc2cc31 |r,TLB:0:4:15.30.14:12| |
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| Structure | 
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