| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50341297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_742583 (CHEMBL1769426) |
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| Ki | 110±n/a nM |
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| Citation |  Zhang, T; Yan, Z; Sromek, A; Knapp, BI; Scrimale, T; Bidlack, JM; Neumeyer, JL Aminothiazolomorphinans with mixed¿ andµ opioid activity. J Med Chem54:1903-13 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50341297 |
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| n/a |
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| Name | BDBM50341297 |
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| Synonyms: | CHEMBL1766035 | N'-(Piperazin-1-yl)-thiazolo[5,4-b]-N-cyclopropylmethylmorphinan |
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| Type | Small organic molecule |
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| Emp. Form. | C25H35N5S |
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| Mol. Mass. | 437.644 |
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| SMILES | C(C1CC1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1cc2sc(NN4CCNCC4)nc2cc31 |r,TLB:0:4:15.30.14:12| |
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| Structure | 
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