| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 15 member 2 |
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| Ligand | BDBM50188479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_762551 (CHEMBL1817008) |
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| Ki | 800±n/a nM |
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| Citation |  Pedretti, A; De Luca, L; Marconi, C; Regazzoni, L; Aldini, G; Vistoli, G Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping. Bioorg Med Chem19:4544-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 15 member 2 |
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| Name: | Solute carrier family 15 member 2 |
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| Synonyms: | Kidney H(+)/peptide cotransporter | Oligopeptide transporter, kidney isoform | PEPT2 | Peptide transporter 2 | S15A2_HUMAN | SLC15A2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 81795.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_762551 |
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| Residue: | 729 |
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| Sequence: | MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSY
YGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLV
YVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEER
TRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSK
IYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALT
RVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFD
FVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLN
LADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHS
VQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVG
EDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIED
IPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIV
LVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMI
KLETKKTKL
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| BDBM50188479 |
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| n/a |
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| Name | BDBM50188479 |
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| Synonyms: | (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid | 2-[1-amino-2-(1H-3-indolyl)-(1S)-ethylcarboxamido]-3-(1H-3-indolyl)-(2S)-propanoic acid | 2-[2-Amino-3-(1H-indol-3-yl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid | CHEMBL286852 | Trp-Trp |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N4O3 |
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| Mol. Mass. | 390.4351 |
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| SMILES | N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O |
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| Structure | 
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